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Pass Word Screen
Go to the cheat screen and enter these.

sparing - get sword
greengoblin - GreenGoblin outfit
megaops - jump higher
thegirlnextdoor - Mary Jane Watson outfit
jungleboy - play as Carvin the Hunter
helipad - play as mini piolet
thepress - play as mr.jamason
sciencerules - play as scientist number 2
lean back - play as thug
myuncle - play as uncle ben
scorpion - Scorpion outfit
killer - unlock all the moves

Unlock Arachnoman
Complete 90 City Events, Collect 90 Tokens & Complete 48 Combat Tours

Unlock Parker Hoodie
Complete 75 City Events, Collect 75 Tokens & Complete 32 Combat Tours

Unlock Peter Parker
Complete 50 City Events, Collect 50 Tokens & Win 4th Race against Johnny Storm

Unlock Spidey Wrestling
Complete 30 City Events & Collect 30 Tokens

Unlock Switch Hero Option on Pause Menu
Complete all Story Missions

Unlock Symbiote Spider-Man (Black Costume)
Complete 100 City Events, Get all Tokens, and finish all Combat Tours

Unlock Venom Races
Complete all Story Missions

Unlock Hard Difficulty
Complete 20 City Events and Complete "Class Trip" Chapter 8.

Unlock Medium Difficulty
Complete 10 City Events and Complete "inexpugnable" Chapter 6.

Unlock Health Bonus & Hard Difficulty Combat Tours
Complete 12 Medium Combat Tours.

Unlock Health Bonus & Medium Difficulty Combat Tours
Complete 8 Easy Combat Tours After Chapter 4 Hell of a Mess.

Unlock Insane Difficulty Combat Tours
Complete all Hard Combat Tours

Remove Police/Military
After you finish the story mode, you can play as Venom; Normally as soon as Venom destroys anything you enter a mini-game and the police/military will try to kill you relentlessly. If you want to go around on a crazed rampage without ever being attacked, just destroy something to activate the mini-game. Then pause the game and go to your "Unlockables" section--the game will warn you that this will exit your mission. Agree to exit the mission and then back out of the Unlockables Section. Now, no matter what you do, the cops will never show up.

Full Health when Life is low
You must have at least one costume for this to work. Go to unlockables,when low on life, them enter costumes. Change costumes then when your back in the game you should have full life.